This is a clinical review of 64 cases of the Adenoid cystic carcinoma who were treated at the Department of Surgery, Presbyterian Medical Center, Chonju during the past 20 years from January, 1971 to December, 1990.
@ES The results were obtained as follows ;
@EN 1) The most common malignant tumor in the minor salivary gland was adenoid cystic carcinoma and its incidence was 59.3%(38 cases).
2) The most common site of adenoid cystic carcinoma in the major salivary grand was parotid gland with the incidence of 23.4%(15 cases).
3) The peak age of patients with adenoid cystic carcinoma was 5th decade(29.6%) and others' peak age except adenoid cystic carcinoma was 6th decade(35.9%).
4) The duration of symptoms of adenoid cystic carcinoma patients was less than one year in the minor salivary gland, comprising 21 cases(55.2%) and more than one year in 17 cases(65.3%) of the major salivary gland carcinoma.
5) According to histologic grade of 64 cases of adenoid cystic carcinoma, Grade I was 15 cases; Grade II, 17 cases; Grade III, 5 cases. Other 27 cases were undetermined.
6) The incidence of cervical lymphnode metastasis of 37 cases of adenoid cystic carcinoma classified into histologic grade was 0% in Grade I, 5.9% in Grade II and 20% in Grade III.
7) The incidence of nerve invasion confirmed histologically was 20% in Grade I, 64.7% in Grade II and 100% in Grade III.
In was significantly difference(p<0.01).
8) The local recurrence rate was 26.7% in Grade I, 47.1% in Grade II and 60% in Grade III. The lung was the commonest site for distant metastasis comprising 14 cases among 19 cases in which distant spread occurred.
9) 5 year determinate disease free survival rate according to the histologic grade was 57.1% in Grade I, 20.0% in 25.0% in Grade III.
10) The determinate 5-year survival rate of adenoid cystic carcinoma was 66.7% in the only curative surgery group, 70.7% in the combined treatment group of surgery and postoperative irradiation, and 33.3% in the non-curative treatment group.
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